Dr. Constantine Kotsanis and his wife, Beverly, celebrated the Kotsanis Institute's 35th anniversary Nov. 15. The business is located at 2260 Pool Road, Grapevine. The clinic provides a patient-centered approach to health that combines traditional and complementary functional medicine with nutrition in what the Kotsanises describe as integrative medicine. Treatment options include cancer care, allergies, pain management, chronic fatigue, learning disorders, food sensitivities, Lyme disease and chronic disorders. 817-481-6342. www.kotsanisinstitute.com