If you drive on Hwy. 288, expect to see a significant road closure this weekend. The northbound lanes of Hwy. 288 will be blocked off in Brazoria County between FM-518 and McHard. The closure will last from Friday at 9 p.m. until Monday at 5 a.m. As an alternate route, take Almeda Drive or Cullen Boulevard. Additionally, on Friday evening, the westbound lanes of Hwy. 290 will be blocked off at Antoine. Detour to Hempstead Highway. From ABC13