As economic development remains a priority for Missouri City city officials, including City Manager Anthony Snipes and Missouri City City Council, the city has seen steady population growth in the last five years. According to newly released data from the U.S. Census Bureau, Missouri City's population as of 2018 was 73,573. Missouri's City's population is up 6.39% from 2014, when the population of the city was 69,152.

In addition to steady population growth, Missouri City residents are also making more money on average. The median annual household income grew from $88,896 in 2017 to $90,335 in 2018.

The city also saw a slight a increase in median home value. The median home value was $171,000 in 2017 and $180,000 in 2018. Additionally, median monthly rent in Missouri City in 2018 was $1,603, while the median monthly mortgage payment was $1,691.

In 2018, 92.1% of Missouri City residents 25 and older had a high school diploma. The percentage of Missouri City residents 25 and older with a bachelor's degree decreased slightly to 44.7% in 2018 from 45.8% in 2017.